Recent studies suggest that >50% of prostate turmours may carry a chromosomal rearrangement on chromosome 21q22.  超过50%的前列腺癌患者携带染色体21q22基因的重排.

The genes involved are the androgen-inducible TMPRSS2 (Transmembrane protease, serine 2 (21q22.3)) and an ETS family transcription factor, ERG (v-ets erythroblastosis virus E26 oncogene like (21q22.2))