Background
The ZytoLight ® SPEC SOX2/CEN 3 Dual Color Probe is designed for the detection of SOX2 gene amplifications frequently observed in squamous cell carcinoma (SCC) of the lung, the esophagus, the oral cavity, and further organ sites. In addition, amplifications and/or overexpression were found in glioma, breast cancer, and other tumor types.
Probe Description
The SPEC SOX2/CEN 3 Dual Color Probe is a mixture of an orange fluorochrome direct labeled CEN 3 probe specific for the alpha satellite centromeric region of chromosome 3 (D3Z1) and a green fluorochrome direct labeled SPEC SOX2 probe specific for the SOX2 gene at 3q26.
Results
In a normal interphase nucleus, two orange and two green signals are expected.Nuclei with amplification of the SOX2 gene locus 3q26 or aneuploidy of chromosome 3 will show multiple copies of the green signal or large green signal clusters.
采购指南
联系电话：010-64484022、64484033,400-699-7909
Z-2127-200 ZytoLight SPEC SOX2/CEN 3 Dual Color Probe 20 (200μl)
相关产品：
Z-2028-20 ZytoLight FISH-Tissue Implementation Kit 20
Incl. Heat Pretreatment Solution Citric, 500 ml; Pepsin Solution, 4 ml; Wash Buffer SSC, 500 ml; 25x Wash Buffer A, 100 ml; DAPI/Antifade-Solution, 0.8 ml
